Antiobesity activity of a sphingosine 1-phosphate analogue FTY720 observed in adipocytes and obese mouse model. [electronic resource]
Producer: 20130513Description: 603-14 p. digitalISSN:- 2092-6413
- 3T3-L1 Cells
- AMP-Activated Protein Kinases -- metabolism
- Adipocytes -- drug effects
- Adipogenesis -- drug effects
- Animals
- Anti-Obesity Agents -- pharmacology
- Antigens, Differentiation -- genetics
- Carrier Proteins -- genetics
- Cell Size
- Diet, High-Fat -- adverse effects
- Disease Models, Animal
- Enzyme Activation
- Fingolimod Hydrochloride
- Gene Expression Regulation, Enzymologic -- drug effects
- Glycogen Synthase Kinase 3 -- genetics
- Lipase -- genetics
- Lipolysis -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Obesity -- etiology
- Perilipin-1
- Phosphoproteins -- genetics
- Phosphorylation
- Propylene Glycols -- pharmacology
- Protein Processing, Post-Translational
- Proto-Oncogene Proteins c-akt -- metabolism
- Sphingosine -- analogs & derivatives
- Sterol Esterase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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