Chemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosome. [electronic resource]
Producer: 20130130Description: 51-64 p. digitalISSN:- 1365-2958
- Amino Acid Sequence
- Animals
- Antiprotozoal Agents -- pharmacology
- Disease Models, Animal
- Enzyme Inhibitors -- pharmacology
- Gene Deletion
- Genes, Essential
- Genes, Protozoan
- Humans
- Kinetics
- Mice
- Models, Molecular
- Molecular Sequence Data
- Phosphorylation
- Protein Conformation
- Pyridoxal -- metabolism
- Pyridoxal Kinase -- antagonists & inhibitors
- Pyridoxamine -- metabolism
- Pyridoxine -- analogs & derivatives
- Sequence Alignment
- Survival Analysis
- Trypanosoma brucei brucei -- enzymology
- Trypanosomiasis, African -- mortality
- Virulence Factors -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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