Furanodiene, a natural product, inhibits breast cancer growth both in vitro and in vivo. [electronic resource]
Producer: 20121213Description: 778-90 p. digitalISSN:- 1421-9778
- Amino Acid Chloromethyl Ketones -- pharmacology
- Animals
- Antineoplastic Agents, Phytogenic -- therapeutic use
- Apoptosis -- drug effects
- Breast Neoplasms -- drug therapy
- Caspase 7 -- metabolism
- Caspase 9 -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Curcuma -- chemistry
- DNA Fragmentation -- drug effects
- Female
- Furans -- therapeutic use
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Heterocyclic Compounds, 2-Ring -- therapeutic use
- Humans
- L-Lactate Dehydrogenase -- metabolism
- MCF-7 Cells
- Membrane Potential, Mitochondrial -- drug effects
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Poly(ADP-ribose) Polymerases -- metabolism
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Transplantation, Heterologous
- bcl-2-Associated X Protein -- metabolism
- bcl-Associated Death Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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