Rho-kinase-dependent pathway mediates the hepatoprotective effects of sorafenib against ischemia/reperfusion liver injury in rats with nonalcoholic steatohepatitis. [electronic resource]
Producer: 20130424Description: 1371-83 p. digitalISSN:- 1527-6473
- Animals
- Apoptosis
- Disease Models, Animal
- Fatty Liver -- therapy
- Gene Expression Regulation, Enzymologic
- Hemodynamics
- Inflammation
- Liver -- drug effects
- MAP Kinase Signaling System
- Male
- Necrosis
- Niacinamide -- analogs & derivatives
- Non-alcoholic Fatty Liver Disease
- Phenylurea Compounds -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- RNA, Messenger -- metabolism
- Rats
- Rats, Sprague-Dawley
- Reperfusion Injury -- drug therapy
- Sorafenib
- Transplantation, Homologous
- rho-Associated Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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