Induction of P-glycoprotein and Bcrp at the rat blood-brain barrier following a subchronic morphine treatment is mediated through NMDA/COX-2 activation. [electronic resource]
Producer: 20121221Description: 491-503 p. digitalISSN:- 1471-4159
- ATP Binding Cassette Transporter, Subfamily B -- genetics
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- genetics
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters -- genetics
- Analysis of Variance
- Animals
- Blood Vessels -- drug effects
- Blood-Brain Barrier -- drug effects
- Brain -- anatomy & histology
- Cell Line, Transformed
- Cyclooxygenase 2 -- metabolism
- Cyclooxygenase Inhibitors -- pharmacology
- Dizocilpine Maleate -- pharmacology
- Dose-Response Relationship, Drug
- Excitatory Amino Acid Antagonists -- pharmacology
- Gene Expression Regulation -- drug effects
- Glutamic Acid -- metabolism
- Humans
- Iloprost -- pharmacology
- Male
- Meloxicam
- Misoprostol -- pharmacology
- Morphine -- administration & dosage
- N-Methylaspartate -- metabolism
- Narcotics -- administration & dosage
- RNA, Messenger -- metabolism
- Rats
- Rats, Sprague-Dawley
- Thiazines -- pharmacology
- Thiazoles -- pharmacology
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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