Plant lectin can target receptors containing sialic acid, exemplified by podoplanin, to inhibit transformed cell growth and migration. [electronic resource]
Producer: 20121128Description: e41845 p. digitalISSN:- 1932-6203
- Amino Acid Sequence
- Animals
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Cell Transformation, Neoplastic
- Dose-Response Relationship, Drug
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Maackia -- chemistry
- Melanoma -- blood supply
- Membrane Glycoproteins -- metabolism
- Mice
- Molecular Sequence Data
- N-Acetylneuraminic Acid -- metabolism
- Necrosis -- chemically induced
- Neovascularization, Pathologic -- diet therapy
- Plant Lectins -- chemistry
- src-Family Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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