Rapid identification of ETP-46992, orally bioavailable PI3K inhibitor, selective versus mTOR. [electronic resource]
Producer: 20121130Description: 5208-14 p. digitalISSN:- 1464-3405
- Administration, Oral
- Animals
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cytochromes -- metabolism
- Disease Models, Animal
- Half-Life
- Humans
- Imidazoles -- chemical synthesis
- Mice
- Mice, Inbred BALB C
- Microsomes, Liver -- metabolism
- Neoplasms -- drug therapy
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Protein Kinase Inhibitors -- chemistry
- Pyrazines -- chemical synthesis
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- Transplantation, Heterologous
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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