Attenuation of high-glucose-induced inflammatory response by a novel curcumin derivative B06 contributes to its protection from diabetic pathogenic changes in rat kidney and heart. [electronic resource]
Producer: 20130524Description: 146-55 p. digitalISSN:- 1873-4847
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Bromobenzenes -- pharmacology
- Curcumin -- analogs & derivatives
- Diabetes Mellitus, Experimental -- complications
- Diabetic Nephropathies -- prevention & control
- Dose-Response Relationship, Drug
- Glucose -- adverse effects
- Heart -- drug effects
- Inflammation -- drug therapy
- Inflammation Mediators -- metabolism
- Interleukin-6 -- metabolism
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Kidney -- drug effects
- Macrophages, Peritoneal -- drug effects
- Male
- Mice
- Mice, Inbred ICR
- Myocardium -- pathology
- NF-kappa B -- metabolism
- Pentanones -- pharmacology
- Protective Agents -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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