The Rho-kinase (ROCK) inhibitor Y-27632 protects against excitotoxicity-induced neuronal death in vivo and in vitro. [electronic resource]
Producer: 20130829Description: 238-48 p. digitalISSN:- 1476-3524
- Amides -- pharmacology
- Animals
- Anticonvulsants -- pharmacology
- Astrocytes -- drug effects
- Cell Death
- Cells, Cultured -- drug effects
- Convulsants -- antagonists & inhibitors
- Glial Fibrillary Acidic Protein
- Glutamic Acid -- toxicity
- Hippocampus -- cytology
- Kainic Acid -- toxicity
- Male
- Mice
- Mice, Inbred ICR
- Myosin Light Chains -- biosynthesis
- Nerve Tissue Proteins -- antagonists & inhibitors
- Neurites -- drug effects
- Neurons -- drug effects
- Neurotoxins -- toxicity
- Protein Kinase Inhibitors -- pharmacology
- Pyridines -- pharmacology
- Seizures -- chemically induced
- Single-Blind Method
- rho GTP-Binding Proteins -- biosynthesis
- rho-Associated Kinases -- antagonists & inhibitors
- rhoA GTP-Binding Protein
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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