The monoclonal antibody CH12 enhances the sorafenib-mediated growth inhibition of hepatocellular carcinoma xenografts expressing epidermal growth factor receptor variant III. [electronic resource]
Producer: 20121113Description: 509-18 p. digitalISSN:- 1476-5586
- Animals
- Antibodies, Monoclonal -- pharmacology
- Antineoplastic Agents -- administration & dosage
- Apoptosis -- drug effects
- Benzenesulfonates -- administration & dosage
- Carcinoma, Hepatocellular -- drug therapy
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Drug Resistance, Neoplasm -- genetics
- Drug Synergism
- ErbB Receptors -- antagonists & inhibitors
- Gene Expression Regulation, Neoplastic
- Humans
- Liver Neoplasms -- genetics
- MAP Kinase Signaling System -- drug effects
- Mice
- Mice, Nude
- Neovascularization, Pathologic -- drug therapy
- Niacinamide -- analogs & derivatives
- Phenylurea Compounds
- Protein Kinase Inhibitors -- administration & dosage
- Proto-Oncogene Proteins c-akt -- metabolism
- Pyridines -- administration & dosage
- STAT3 Transcription Factor -- metabolism
- Sorafenib
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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