Inhibition of CK2α down-regulates Hedgehog/Gli signaling leading to a reduction of a stem-like side population in human lung cancer cells. [electronic resource]
Producer: 20121127Description: e38996 p. digitalISSN:- 1932-6203
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters -- metabolism
- Carcinoma, Non-Small-Cell Lung -- genetics
- Casein Kinase II -- antagonists & inhibitors
- Cell Count
- Cell Line, Tumor
- Down-Regulation -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Gene Knockdown Techniques
- Gene Silencing -- drug effects
- Humans
- Lung Neoplasms -- genetics
- Neoplasm Proteins -- metabolism
- Neoplastic Stem Cells -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Proteolysis -- drug effects
- Side-Population Cells -- drug effects
- Signal Transduction -- genetics
- Small Molecule Libraries -- pharmacology
- Transcription Factors -- genetics
- Transcription, Genetic -- drug effects
- Transcriptional Activation -- drug effects
- Up-Regulation -- drug effects
- Zinc Finger Protein GLI1
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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