Targeting tumour proliferation with a small-molecule inhibitor of AICAR transformylase homodimerization. [electronic resource]
Producer: 20130610Description: 1628-34 p. digitalISSN:- 1439-7633
- Antineoplastic Agents -- chemical synthesis
- Breast Neoplasms -- drug therapy
- Catalytic Domain -- drug effects
- Cell Count
- Cell Division -- drug effects
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Enzyme Inhibitors -- chemical synthesis
- Female
- High-Throughput Screening Assays
- Humans
- MCF-7 Cells
- Molecular Structure
- Molecular Weight
- Peptides, Cyclic -- chemical synthesis
- Phosphoribosylaminoimidazolecarboxamide Formyltransferase -- antagonists & inhibitors
- Protein Multimerization -- drug effects
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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