Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: involvement in Smad activation and NF-κB inhibition. [electronic resource]
Producer: 20121218Description: 905-13 p. digitalISSN:- 1757-9708
- Animals
- Bone and Bones -- drug effects
- Cell Differentiation
- Cell Line
- Cellular Senescence
- Curcumin -- analogs & derivatives
- Dose-Response Relationship, Drug
- Drug Design
- Gene Expression Regulation
- Luciferases -- metabolism
- Mice
- Models, Chemical
- NF-kappa B -- metabolism
- NIH 3T3 Cells
- Osteoblasts -- cytology
- Osteoclasts -- cytology
- Piperidones -- pharmacology
- Pyridines
- RANK Ligand -- metabolism
- Signal Transduction
- Smad4 Protein -- metabolism
- Tumor Necrosis Factor-alpha -- biosynthesis
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Publication Type: Journal Article
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