Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo. [electronic resource]
Producer: 20131030Description: 2433-41 p. digitalISSN:- 1476-5594
- Animals
- Cell Line, Tumor
- ErbB Receptors -- biosynthesis
- Female
- Gene Knockdown Techniques
- HEK293 Cells
- Humans
- Mice
- Mice, Inbred BALB C
- Neoplasms -- genetics
- Phosphorylation
- RNA, Small Interfering -- administration & dosage
- STAT3 Transcription Factor -- genetics
- Signal Transduction
- Smad7 Protein -- genetics
- Transfection
- Transforming Growth Factor beta -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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