Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis. [electronic resource]
Producer: 20121017Description: 669-80 p. digitalISSN:- 1470-8736
- Analysis of Variance
- Animals
- Arachidonic Acid -- metabolism
- Benzofurans -- pharmacology
- Choline -- metabolism
- Clodronic Acid -- pharmacology
- DNA Primers -- genetics
- Diet, High-Fat
- Fatty Acids, Unsaturated -- metabolism
- Fatty Liver -- complications
- Gadolinium -- pharmacology
- Hemodynamics
- Hypertension, Portal -- etiology
- Insulin Resistance -- physiology
- Kupffer Cells -- drug effects
- Leptin -- blood
- Methionine -- deficiency
- Methoxamine -- metabolism
- Microcirculation -- physiology
- Non-alcoholic Fatty Liver Disease
- Oxidative Stress -- physiology
- RNA, Messenger -- metabolism
- Rats
- Receptors, Thromboxane A2, Prostaglandin H2 -- antagonists & inhibitors
- Sulfonylurea Compounds -- pharmacology
- Thiobarbituric Acid Reactive Substances -- metabolism
- Thromboxane A2 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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