Dimethyl fumarate inhibits dendritic cell maturation via nuclear factor κB (NF-κB) and extracellular signal-regulated kinase 1 and 2 (ERK1/2) and mitogen stress-activated kinase 1 (MSK1) signaling. [electronic resource]
Producer: 20121105Description: 28017-26 p. digitalISSN:- 1083-351X
- Animals
- B7-1 Antigen -- biosynthesis
- B7-2 Antigen -- biosynthesis
- Cell Differentiation -- drug effects
- Cells, Cultured
- Dendritic Cells -- cytology
- Dimethyl Fumarate
- Fumarates -- pharmacology
- Histocompatibility Antigens Class II -- biosynthesis
- Immunosuppressive Agents -- pharmacology
- Interleukin-12 -- immunology
- Interleukin-6 -- immunology
- MAP Kinase Signaling System -- drug effects
- Mice
- Mitogen-Activated Protein Kinase 3 -- immunology
- Phosphorylation -- drug effects
- Ribosomal Protein S6 Kinases, 90-kDa -- immunology
- Th1 Cells -- cytology
- Th17 Cells -- cytology
- Transcription Factor RelA -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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