Process for immune defect and chromosomal translocation during early thymocyte development lacking ATM. [electronic resource]
Producer: 20121009Description: 789-99 p. digitalISSN:- 1528-0020
- Animals
- Apoptosis
- Ataxia Telangiectasia Mutated Proteins
- Blotting, Western
- Bone Marrow Transplantation
- CD4-Positive T-Lymphocytes -- immunology
- CD8-Positive T-Lymphocytes -- immunology
- Cell Cycle
- Cell Cycle Proteins -- physiology
- Cell Differentiation
- Cell Proliferation
- DNA-Binding Proteins -- physiology
- Female
- Flow Cytometry
- Gene Rearrangement, T-Lymphocyte
- Genomic Instability
- In Situ Hybridization, Fluorescence
- Karyotyping
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Knockout
- Protein Serine-Threonine Kinases -- physiology
- RNA, Messenger -- genetics
- Real-Time Polymerase Chain Reaction
- Receptors, Antigen, T-Cell, alpha-beta -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Thymocytes -- immunology
- Translocation, Genetic
- Tumor Suppressor Proteins -- physiology
- V(D)J Recombination
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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