Pimaric acid from Aralia cordata has an inhibitory effect on TNF-α-induced MMP-9 production and HASMC migration via down-regulated NF-κB and AP-1. [electronic resource]
Producer: 20121106Description: 112-9 p. digitalISSN:- 1872-7786
- Anti-Inflammatory Agents -- isolation & purification
- Aorta -- cytology
- Aralia -- chemistry
- Cell Line
- Cell Movement -- drug effects
- Diterpenes -- isolation & purification
- Down-Regulation -- drug effects
- Humans
- MAP Kinase Signaling System -- drug effects
- Matrix Metalloproteinase 9 -- genetics
- Muscle, Smooth, Vascular -- cytology
- Myocytes, Smooth Muscle -- cytology
- NF-kappa B -- analysis
- Phosphorylation -- drug effects
- Transcription Factor AP-1 -- analysis
- Tumor Necrosis Factor-alpha -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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