Age-dependent therapeutic effect of memantine in a mouse model of juvenile Batten disease. [electronic resource]
Producer: 20130114Description: 769-75 p. digitalISSN:- 1873-7064
- Aging
- Animals
- Cerebral Cortex -- drug effects
- Disease Models, Animal
- Disease Progression
- Dose-Response Relationship, Drug
- Drug Resistance
- Excitatory Amino Acid Antagonists -- administration & dosage
- Female
- Male
- Memantine -- administration & dosage
- Membrane Glycoproteins -- genetics
- Mice
- Mice, 129 Strain
- Mice, Knockout
- Molecular Chaperones -- genetics
- Molecular Targeted Therapy
- Motor Skills -- drug effects
- Nerve Tissue Proteins -- antagonists & inhibitors
- Neuronal Ceroid-Lipofuscinoses -- drug therapy
- Neurons -- drug effects
- Organ Specificity
- Receptors, N-Methyl-D-Aspartate -- antagonists & inhibitors
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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