LRRK2 kinase activity mediates toxic interactions between genetic mutation and oxidative stress in a Drosophila model: suppression by curcumin. [electronic resource]
Producer: 20121129Description: 385-92 p. digitalISSN:- 1095-953X
- Analysis of Variance
- Animals
- Animals, Genetically Modified
- Cell Survival -- drug effects
- Cerebral Cortex -- cytology
- Curcumin -- pharmacology
- Dopamine -- metabolism
- Drosophila
- Drosophila Proteins -- genetics
- Drug Interactions
- Enzyme Inhibitors -- pharmacology
- Gene Expression Regulation -- drug effects
- Green Fluorescent Proteins -- metabolism
- Humans
- Hydrogen Peroxide -- pharmacology
- Immunoprecipitation
- Indoles -- pharmacology
- Mice
- Models, Animal
- Motor Activity -- drug effects
- Mutation -- genetics
- Neurons -- drug effects
- Oxidants -- pharmacology
- Oxidation-Reduction -- drug effects
- Phenols -- pharmacology
- Phosphorylation -- drug effects
- Protein Serine-Threonine Kinases -- drug effects
- Survival Analysis
- Transfection
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Publication Type: Journal Article
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