Knockdown of cytochrome P450 2E1 inhibits oxidative stress and apoptosis in the cTnT(R141W) dilated cardiomyopathy transgenic mice. [electronic resource]
Producer: 20120907Description: 81-9 p. digitalISSN:- 1524-4563
- Amino Acid Substitution
- Animals
- Apoptosis -- genetics
- Cardiomyopathy, Dilated -- chemically induced
- Cytochrome P-450 CYP2E1 -- genetics
- Cytochromes c -- metabolism
- Doxorubicin
- Echocardiography
- Glutathione -- metabolism
- HEK293 Cells
- Heart Ventricles -- diagnostic imaging
- Humans
- Hydrogen Peroxide -- metabolism
- Immunoblotting
- Kaplan-Meier Estimate
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Microscopy, Electron, Transmission
- Mitochondria, Heart -- metabolism
- Myocardium -- metabolism
- Oxidative Stress
- RNA Interference
- Reverse Transcriptase Polymerase Chain Reaction
- Troponin T -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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