Tyrphostin AG490 agent modestly but significantly prevents onset of type 1 in NOD mouse; implication of immunologic and metabolic effects of a Jak-Stat pathway inhibitor. [electronic resource]
Producer: 20130130Description: 1038-47 p. digitalISSN:- 1573-2592
- Animals
- Blood Glucose -- analysis
- Bone Marrow Cells -- cytology
- CD4-Positive T-Lymphocytes -- immunology
- Cells, Cultured
- Dendritic Cells
- Diabetes Mellitus, Type 1 -- blood
- Female
- Forkhead Transcription Factors -- immunology
- Interleukin-2 Receptor alpha Subunit -- immunology
- Mice
- Mice, Inbred BALB C
- Mice, Inbred NOD
- PPAR gamma -- immunology
- Protein Kinase Inhibitors -- therapeutic use
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- STAT Transcription Factors -- immunology
- Tyrphostins -- therapeutic use
No physical items for this record
Publication Type: Journal Article; Research Support, American Recovery and Reinvestment Act; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.