Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin αvβ5-induced secretion of VEGF-A. [electronic resource]
Producer: 20121126Description: 693-705 p. digitalISSN:- 1525-2191
- Adult
- Animals
- Cell Line, Tumor
- Cell Membrane -- metabolism
- Endothelium, Vascular -- enzymology
- Enzyme Activation
- Gene Expression Regulation, Neoplastic
- Gene Knockdown Techniques
- Humans
- Male
- Matrix Metalloproteinase 14 -- metabolism
- Matrix Metalloproteinase 2 -- metabolism
- Melanoma -- blood supply
- Mice
- Models, Biological
- Neoplasm Invasiveness
- Neovascularization, Pathologic -- genetics
- Phosphatidylinositol 3-Kinases -- metabolism
- RNA, Messenger -- genetics
- Receptors, Vitronectin -- metabolism
- Signal Transduction
- Skin Neoplasms -- blood supply
- Vascular Endothelial Growth Factor A -- genetics
- Vascular Endothelial Growth Factor Receptor-2 -- metabolism
- von Willebrand Factor -- metabolism
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.