PEGylation of interleukin-10 improves the pharmacokinetic profile and enhances the antifibrotic effectivity in CCl₄-induced fibrogenesis in mice. [electronic resource]
Producer: 20130102Description: 84-91 p. digitalISSN:- 1873-4995
- Animals
- Carbon Tetrachloride
- Cell Line
- Collagen -- metabolism
- Half-Life
- Humans
- Interleukin-10 -- chemistry
- Interleukin-1beta -- genetics
- Interleukin-6 -- genetics
- Liver -- drug effects
- Liver Cirrhosis -- chemically induced
- Macrophages -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Polyethylene Glycols -- chemistry
- Transcriptional Activation -- drug effects
- Tumor Necrosis Factor-alpha -- immunology
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Publication Type: Journal Article
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