A new protoapigenone analog RY10-4 induces apoptosis and suppresses invasion through the PI3K/Akt pathway in human breast cancer. [electronic resource]
Producer: 20121010Description: 210-20 p. digitalISSN:- 1872-7980
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Blotting, Western
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Female
- Humans
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Neoplasm Invasiveness
- Phosphatidylinositol 3-Kinase -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Pyrones -- pharmacology
- S Phase Cell Cycle Checkpoints -- drug effects
- Signal Transduction -- drug effects
- Time Factors
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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