Phase I pharmacokinetic study of chronomodulated dose-intensified combination of capecitabine and oxaliplatin (XELOX) in metastatic colorectal cancer. [electronic resource]
Producer: 20120924Description: 141-50 p. digitalISSN:- 1432-0843
- Adult
- Aged
- Aged, 80 and over
- Anemia -- chemically induced
- Antineoplastic Combined Chemotherapy Protocols -- adverse effects
- Area Under Curve
- Capecitabine
- Colorectal Neoplasms -- drug therapy
- Deoxycytidine -- administration & dosage
- Diarrhea -- chemically induced
- Dose-Response Relationship, Drug
- Drug Administration Schedule
- Female
- Fluorouracil -- administration & dosage
- Humans
- Kaplan-Meier Estimate
- Male
- Metabolic Clearance Rate
- Middle Aged
- Neoplasm Metastasis
- Organoplatinum Compounds -- administration & dosage
- Oxaliplatin
- Treatment Outcome
- Vomiting -- chemically induced
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Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
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