A role for the epidermal growth factor receptor signaling in development of intestinal serrated polyps in mice and humans. [electronic resource]
Producer: 20121106Description: 730-740 p. digitalISSN:- 1528-0012
- Adenoma -- genetics
- Animals
- Blotting, Western
- Caco-2 Cells
- Colonoscopy
- Enzyme Activation
- ErbB Receptors -- antagonists & inhibitors
- Heparin-binding EGF-like Growth Factor
- Humans
- Hyperplasia
- Immunohistochemistry
- Intercellular Signaling Peptides and Proteins -- genetics
- Intestinal Mucosa -- drug effects
- Intestinal Neoplasms -- genetics
- Intestinal Polyps -- genetics
- Ligands
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mitogen-Activated Protein Kinase 1 -- antagonists & inhibitors
- Mitogen-Activated Protein Kinase 3 -- antagonists & inhibitors
- Mutation
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins B-raf -- genetics
- Proto-Oncogene Proteins p21(ras)
- Receptors, G-Protein-Coupled -- genetics
- Recombinant Fusion Proteins -- metabolism
- Signal Transduction -- drug effects
- Transfection
- ras Proteins -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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