The FKBP-rapamycin binding domain of human TOR undergoes strong conformational changes in the presence of membrane mimetics with and without the regulator phosphatidic acid. [electronic resource]
Producer: 20120905Description: 4909-21 p. digitalISSN:- 1520-4995
- Cell Membrane -- chemistry
- Humans
- Liposomes -- pharmacology
- Micelles
- Models, Molecular
- Phosphatidic Acids -- pharmacology
- Protein Structure, Secondary -- drug effects
- Protein Structure, Tertiary -- drug effects
- Sirolimus -- metabolism
- TOR Serine-Threonine Kinases -- chemistry
- Tacrolimus Binding Protein 1A -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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