The Gly(972)Arg variant of human IRS1 gene is associated with variation in glomerular filtration rate likely through impaired insulin receptor signaling. [electronic resource]
Producer: 20121105Description: 2385-93 p. digitalISSN:- 1939-327X
- Adult
- Diabetes Mellitus, Type 2 -- genetics
- Female
- Genotype
- Glomerular Filtration Rate -- genetics
- Humans
- Insulin
- Insulin Receptor Substrate Proteins -- genetics
- Linkage Disequilibrium
- Male
- Mexican Americans -- genetics
- Middle Aged
- Phenotype
- Polymorphism, Single Nucleotide
- Proto-Oncogene Proteins c-akt -- metabolism
- Receptor, Insulin -- genetics
- Signal Transduction -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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