E2F1-dependent pathways are involved in amonafide analogue 7-d-induced DNA damage, G2/M arrest, and apoptosis in p53-deficient K562 cells. [electronic resource]
Producer: 20130107Description: 3165-77 p. digitalISSN:- 1097-4644
- Adenine
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Apoptotic Protease-Activating Factor 1 -- genetics
- Ataxia Telangiectasia Mutated Proteins
- Blotting, Western
- Caffeine -- pharmacology
- Cell Cycle Proteins -- antagonists & inhibitors
- Comet Assay
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- DNA Breaks, Double-Stranded
- Dose-Response Relationship, Drug
- E2F1 Transcription Factor -- genetics
- Flow Cytometry
- G2 Phase Cell Cycle Checkpoints
- Gene Knockout Techniques -- methods
- HCT116 Cells
- HeLa Cells
- Hep G2 Cells
- Humans
- Inhibitory Concentration 50
- K562 Cells
- M Phase Cell Cycle Checkpoints
- MCF-7 Cells
- Naphthalimides -- pharmacology
- Organophosphonates
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Rats
- Signal Transduction
- Time Factors
- Tumor Suppressor Protein p53 -- genetics
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.