Prostate-targeted biodegradable nanoparticles loaded with androgen receptor silencing constructs eradicate xenograft tumors in mice. [electronic resource]
Producer: 20130211Description: 1297-309 p. digitalISSN:- 1748-6963
- Animals
- Aptamers, Nucleotide -- chemistry
- Cell Line, Tumor
- Drug Delivery Systems
- Genetic Therapy
- Humans
- Lactic Acid -- chemistry
- Male
- Mice
- Mice, Nude
- Nanoparticles -- chemistry
- Polyglycolic Acid -- chemistry
- Polylactic Acid-Polyglycolic Acid Copolymer
- Prostate -- metabolism
- Prostate-Specific Antigen -- blood
- Prostatic Neoplasms -- genetics
- RNA Interference
- RNA, Small Interfering -- administration & dosage
- Receptors, Androgen -- genetics
- Transplantation, Heterologous
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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