Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency. [electronic resource]
Producer: 20121113Description: 2069-78 p. digitalISSN:- 1476-5551
- Animals
- Animals, Genetically Modified
- Apoptosis
- Biomarkers, Tumor -- genetics
- Blotting, Western
- Cell Line, Tumor
- Cell Proliferation
- Cell Transformation, Neoplastic
- Gene Expression Profiling
- Gene Expression Regulation, Leukemic
- Humans
- Mice
- Oligonucleotide Array Sequence Analysis
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma -- metabolism
- Proto-Oncogene Proteins c-myc -- metabolism
- RNA, Messenger -- genetics
- Real-Time Polymerase Chain Reaction
- Receptor, Notch1 -- physiology
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Thymocytes
- Zebrafish -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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