In vitro PLK1 inhibition by BI 2536 decreases proliferation and induces cell-cycle arrest in melanoma cells. [electronic resource]
Producer: 20120815Description: 587-92 p. digitalISSN:- 1545-9616
- Antineoplastic Agents -- administration & dosage
- Cell Cycle Proteins -- antagonists & inhibitors
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Disease Progression
- Dose-Response Relationship, Drug
- G2 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- M Phase Cell Cycle Checkpoints -- drug effects
- Melanoma -- drug therapy
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins -- antagonists & inhibitors
- Pteridines -- administration & dosage
- Skin Neoplasms -- drug therapy
- Polo-Like Kinase 1
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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