Antileukemia component, dehydroeburicoic acid from Antrodia camphorata induces DNA damage and apoptosis in vitro and in vivo models. [electronic resource]
Producer: 20121204Description: 788-96 p. digitalISSN:- 1618-095X
- Animals
- Antineoplastic Agents -- pharmacology
- Antrodia -- chemistry
- Apoptosis -- drug effects
- Checkpoint Kinase 2
- Chromatography, High Pressure Liquid
- DNA Damage -- drug effects
- Drug Screening Assays, Antitumor
- Ergosterol -- analogs & derivatives
- Female
- HL-60 Cells
- Histones -- metabolism
- Humans
- Lanosterol -- analogs & derivatives
- Leukemia -- drug therapy
- Medicine, Chinese Traditional
- Mice
- Mice, Nude
- Phosphorylation
- Protein Serine-Threonine Kinases -- metabolism
- Topoisomerase II Inhibitors -- chemistry
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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