Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling. [electronic resource]
Producer: 20120716Description: 547-54 p. digitalISSN:- 1552-4469
- Animals
- Catalytic Domain
- Cell Culture Techniques
- Cell Nucleus -- drug effects
- Cytoplasm -- drug effects
- DNA-Activated Protein Kinase -- genetics
- Electrophoresis, Polyacrylamide Gel
- Embryo, Nonmammalian -- enzymology
- HeLa Cells
- Humans
- Immunoprecipitation
- Interferon-gamma -- pharmacology
- Microscopy, Confocal
- Models, Molecular
- Phosphorylation
- Poly (ADP-Ribose) Polymerase-1
- Poly(ADP-ribose) Polymerases -- genetics
- Protein Interaction Maps
- Signal Transduction -- drug effects
- Transfection
- Tryptophan-tRNA Ligase -- genetics
- Tumor Suppressor Protein p53 -- genetics
- Zebrafish -- embryology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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