Novel phosphoramidate prodrugs of N-acetyl-(D)-glucosamine with antidegenerative activity on bovine and human cartilage explants. [electronic resource]
Producer: 20120907Description: 4629-39 p. digitalISSN:- 1520-4804
- Acetylglucosamine -- analogs & derivatives
- Aggrecans -- metabolism
- Animals
- Cartilage, Articular -- drug effects
- Cattle
- Chondrocytes -- drug effects
- Drug Stability
- Glycosaminoglycans -- metabolism
- Guinea Pigs
- Half-Life
- Humans
- Organ Culture Techniques
- Organophosphorus Compounds -- chemical synthesis
- Osteoarthritis -- drug therapy
- Prodrugs -- chemical synthesis
- Stereoisomerism
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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