Olmesartan medoxomil treatment potently improves cardiac myosin-induced dilated cardiomyopathy via the modulation of ACE-2 and ANG 1-7 mas receptor. [electronic resource]
Producer: 20121102Description: 850-60 p. digitalISSN:- 1029-2470
- Angiotensin I -- metabolism
- Angiotensin II Type 1 Receptor Blockers -- administration & dosage
- Angiotensin-Converting Enzyme 2
- Animals
- Biomarkers -- metabolism
- Cardiac Myosins -- administration & dosage
- Cardiomyopathy, Dilated -- chemically induced
- Endopeptidases -- metabolism
- Fibrosis -- prevention & control
- Gene Expression Regulation -- drug effects
- Heart -- drug effects
- Hypertrophy, Left Ventricular -- prevention & control
- Imidazoles -- administration & dosage
- Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Olmesartan Medoxomil
- Peptide Fragments -- metabolism
- Peptidyl-Dipeptidase A -- genetics
- Proto-Oncogene Mas
- Proto-Oncogene Proteins -- antagonists & inhibitors
- RNA, Messenger -- biosynthesis
- Rats
- Receptors, G-Protein-Coupled -- antagonists & inhibitors
- Tetrazoles -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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