A murine monoclonal antibody directed against the carboxyl-terminal domain of GRP78 suppresses melanoma growth in mice. [electronic resource]
Producer: 20120827Description: 225-35 p. digitalISSN:- 1473-5636
- Animals
- Antibodies, Monoclonal -- biosynthesis
- Antibody Affinity
- Antibody Specificity
- Antineoplastic Agents -- metabolism
- Apoptosis -- drug effects
- Dose-Response Relationship, Drug
- Endoplasmic Reticulum Chaperone BiP
- Enzyme-Linked Immunosorbent Assay
- Epitope Mapping
- Epitopes
- Female
- Flow Cytometry
- Heat-Shock Proteins -- chemistry
- Hep G2 Cells
- Humans
- Hybridomas
- Melanoma, Experimental -- drug therapy
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Phosphatidylinositol 3-Kinase -- metabolism
- Phosphorylation
- Protein Structure, Tertiary
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- Time Factors
- Tumor Burden
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Publication Type: Comparative Study; Journal Article
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