Neuroprotection by the soy isoflavone, genistein, via inhibition of mitochondria-dependent apoptosis pathways and reactive oxygen induced-NF-κB activation in a cerebral ischemia mouse model. [electronic resource]
Producer: 20121012Description: 759-67 p. digitalISSN:- 1872-9754
- Animals
- Apoptosis -- drug effects
- Blotting, Western
- Brain Ischemia -- enzymology
- Caspase 3 -- metabolism
- Cytochromes c -- metabolism
- Disease Models, Animal
- Enzyme Activation
- Genistein -- pharmacology
- Glutathione Peroxidase -- metabolism
- In Situ Nick-End Labeling
- Lipid Peroxidation
- Male
- Mice
- Mice, Inbred C57BL
- Mitochondria -- drug effects
- NF-kappa B -- metabolism
- Neuroprotective Agents -- pharmacology
- Reactive Oxygen Species -- metabolism
- Superoxide Dismutase
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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