Waon therapy upregulates Hsp90 and leads to angiogenesis through the Akt-endothelial nitric oxide synthase pathway in mouse hindlimb ischemia. [electronic resource]
Producer: 20121012Description: 1712-21 p. digitalISSN:- 1347-4820
- Angiogenic Proteins -- metabolism
- Animals
- Apolipoproteins E -- deficiency
- Arteries -- enzymology
- Benzoquinones -- pharmacology
- Blood Flow Velocity
- Capillaries -- enzymology
- Disease Models, Animal
- Endothelial Cells -- enzymology
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Hindlimb
- Hyperthermia, Induced
- Immunohistochemistry
- Ischemia -- enzymology
- Lactams, Macrocyclic -- pharmacology
- Laser-Doppler Flowmetry
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Muscle, Skeletal -- blood supply
- Neovascularization, Physiologic -- drug effects
- Nitric Oxide -- metabolism
- Nitric Oxide Synthase Type III -- metabolism
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- metabolism
- Regional Blood Flow
- Signal Transduction -- drug effects
- Time Factors
- Up-Regulation
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Publication Type: Journal Article
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