Rapamycin is less fibrogenic than Cyclosporin A as demonstrated in a rat model of chronic allograft nephropathy. [electronic resource]
Producer: 20130402Description: e255-63 p. digitalISSN:- 1095-8673
- Animals
- Cadherins -- metabolism
- Connective Tissue Growth Factor -- metabolism
- Creatinine -- blood
- Cyclosporine -- adverse effects
- Epithelial-Mesenchymal Transition
- Fibrosis
- Graft Rejection -- immunology
- Immunosuppressive Agents -- adverse effects
- Kidney -- drug effects
- Kidney Transplantation -- immunology
- Male
- Models, Animal
- Rats
- Rats, Inbred F344
- Rats, Inbred Lew
- Renal Insufficiency, Chronic -- metabolism
- Sirolimus -- adverse effects
- Transplantation, Homologous
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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