Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells. [electronic resource]
Producer: 20120904Description: e1002566 p. digitalISSN:- 1553-7404
- Animals
- Cell Cycle Checkpoints -- genetics
- Cell Cycle Proteins -- genetics
- Cell Proliferation
- Centrosome -- metabolism
- Cerebral Cortex -- abnormalities
- Gene Expression Regulation, Developmental
- HeLa Cells
- Humans
- Intracellular Signaling Peptides and Proteins
- M Phase Cell Cycle Checkpoints -- genetics
- Mandibulofacial Dysostosis -- genetics
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mice, Mutant Strains
- Mitosis -- genetics
- Neurogenesis -- genetics
- Neurons -- cytology
- Nuclear Proteins -- genetics
- Phosphoproteins -- genetics
- Protein Serine-Threonine Kinases -- genetics
- Proto-Oncogene Proteins -- genetics
- Stem Cells -- cytology
- Polo-Like Kinase 1
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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