Cross-regulations among NRFs and KEAP1 and effects of their silencing on arsenic-induced antioxidant response and cytotoxicity in human keratinocytes. [electronic resource]
Producer: 20120731Description: 583-9 p. digitalISSN:- 1552-9924
- Antioxidants -- metabolism
- Apoptosis
- Arsenic -- pharmacology
- Arsenites -- pharmacology
- Blotting, Western
- Cell Line
- Dose-Response Relationship, Drug
- Environmental Pollutants -- toxicity
- Flow Cytometry
- Gene Knockdown Techniques
- Humans
- Intracellular Signaling Peptides and Proteins -- genetics
- Kelch-Like ECH-Associated Protein 1
- Keratinocytes -- cytology
- Lentivirus
- NF-E2-Related Factor 1 -- genetics
- NF-E2-Related Factor 2 -- genetics
- Oxidative Stress
- RNA, Small Interfering -- metabolism
- Real-Time Polymerase Chain Reaction
- Reverse Transcriptase Polymerase Chain Reaction
- Skin Diseases -- chemically induced
- Sodium Compounds -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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