The heat shock protein 90 inhibitor SNX-2112 inhibits B16 melanoma cell growth in vitro and in vivo. [electronic resource]
Producer: 20120827Description: 1904-10 p. digitalISSN:- 1791-2431
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Glycogen Synthase Kinase 3 -- antagonists & inhibitors
- Glycogen Synthase Kinase 3 beta
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Heterocyclic Compounds, 4 or More Rings -- pharmacology
- I-kappa B Kinase -- antagonists & inhibitors
- Melanoma, Experimental -- drug therapy
- Mice
- Mice, Inbred C57BL
- Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- NF-kappa B -- drug effects
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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