Synthetic retinoid CD437 induces apoptosis and acts synergistically with TRAIL receptor-2 agonist in malignant melanoma. [electronic resource]
Producer: 20120601Description: 516-22 p. digitalISSN:- 1090-2104
- Antibodies, Monoclonal -- pharmacology
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Caspase 8 -- metabolism
- Caspase 9 -- metabolism
- Cathepsin D -- metabolism
- Cell Line, Tumor
- Cell Survival -- drug effects
- Drug Synergism
- Humans
- Melanoma -- metabolism
- Poly(ADP-ribose) Polymerases -- metabolism
- RNA, Messenger -- biosynthesis
- Receptors, TNF-Related Apoptosis-Inducing Ligand -- agonists
- Retinoids -- pharmacology
- Skin Neoplasms -- metabolism
- Transcription Factor CHOP -- biosynthesis
- Up-Regulation
- fas Receptor -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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