Chk1 suppresses bypass of mitosis and tetraploidization in p53-deficient cancer cells. [electronic resource]
Producer: 20120914Description: 1564-72 p. digitalISSN:- 1551-4005
- Alleles
- Ataxia Telangiectasia Mutated Proteins
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- Checkpoint Kinase 1
- DNA Damage
- Diploidy
- HCT116 Cells
- Haploinsufficiency
- Homologous Recombination
- Humans
- Metaphase
- Mitosis
- Mutation
- Protein Kinases -- metabolism
- Protein Serine-Threonine Kinases -- genetics
- RNA Interference
- Tetraploidy
- Tumor Suppressor Protein p53 -- deficiency
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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