A novel library screen identifies immunosuppressors that promote osteoblast differentiation. [electronic resource]
Producer: 20120913Description: 1294-303 p. digitalISSN:- 1873-2763
- 3T3 Cells
- Animals
- Bone Morphogenetic Protein 2 -- administration & dosage
- Bone Remodeling -- drug effects
- Cell Differentiation -- drug effects
- Cell Line
- Core Binding Factor Alpha 1 Subunit -- genetics
- Drug Evaluation, Preclinical -- methods
- Drug Synergism
- High-Throughput Screening Assays -- methods
- Immunosuppressive Agents -- administration & dosage
- Mice
- Osteoblasts -- cytology
- RNA, Messenger -- genetics
- Signal Transduction -- drug effects
- Sirolimus -- administration & dosage
- Smad7 Protein -- genetics
- Small Molecule Libraries -- administration & dosage
- Sp7 Transcription Factor
- Tacrolimus -- administration & dosage
- Transcription Factors -- genetics
- Transforming Growth Factor beta1 -- administration & dosage
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Publication Type: Comparative Study; Evaluation Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Validation Study
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