An evaluation of gene-gene interaction between the CYP2C9 and VKORC1 genotypes affecting the anticoagulant effect of phenprocoumon and acenocoumarol. [electronic resource]
Producer: 20120830Description: 767-72 p. digitalISSN:- 1538-7836
- Acenocoumarol -- adverse effects
- Adult
- Aged
- Aged, 80 and over
- Anticoagulants -- adverse effects
- Aryl Hydrocarbon Hydroxylases -- genetics
- Blood Coagulation -- drug effects
- Cytochrome P-450 CYP2C9
- Drug Monitoring -- methods
- Female
- Genotype
- Humans
- International Normalized Ratio
- Linear Models
- Male
- Middle Aged
- Mixed Function Oxygenases -- genetics
- Netherlands
- Pharmacogenetics
- Phenotype
- Phenprocoumon -- adverse effects
- Proportional Hazards Models
- Vitamin K Epoxide Reductases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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