Curcumin protects against regional myocardial ischemia/reperfusion injury through activation of RISK/GSK-3β and inhibition of p38 MAPK and JNK. [electronic resource]
Producer: 20130418Description: 387-94 p. digitalISSN:- 1940-4034
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- antagonists & inhibitors
- Antioxidants -- chemistry
- Cardiotonic Agents -- antagonists & inhibitors
- Curcumin -- chemistry
- Drug Therapy, Combination
- Enzyme Inhibitors -- adverse effects
- Glycogen Synthase Kinase 3 -- antagonists & inhibitors
- Glycogen Synthase Kinase 3 beta
- Heart Ventricles -- drug effects
- Indoles -- therapeutic use
- MAP Kinase Signaling System -- drug effects
- Male
- Maleimides -- therapeutic use
- Myocardial Infarction -- etiology
- Myocardial Reperfusion Injury -- enzymology
- Phosphatidylinositol 3-Kinase -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation -- drug effects
- Protein Processing, Post-Translational -- drug effects
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Rats
- Rats, Sprague-Dawley
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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