Low dose IR-induced IGF-1-sCLU expression: a p53-repressed expression cascade that interferes with TGFβ1 signaling to confer a pro-survival bystander effect. [electronic resource]
Producer: 20130604Description: 479-90 p. digitalISSN:- 1476-5594
- Animals
- Apoptosis -- genetics
- Bone Marrow -- metabolism
- Cell Line, Tumor
- Clusterin -- genetics
- Colon -- metabolism
- Epithelial Cells -- metabolism
- Female
- Gamma Rays
- HCT116 Cells
- Humans
- Insulin-Like Growth Factor I -- genetics
- MCF-7 Cells
- Male
- Mice
- Mice, Transgenic
- Molecular Chaperones -- genetics
- Promoter Regions, Genetic
- Signal Transduction -- radiation effects
- Smad Proteins -- genetics
- Transforming Growth Factor beta1 -- genetics
- Tumor Suppressor Protein p53 -- genetics
- Whole-Body Irradiation
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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